-- Use mobile management to try to limit LTE use, although unless Apple expands the iOS mobile management functionality in iOS 6 (more on that in a bit), there aren't that many options for curtailing data use. That said, some mobile management solutions can track data use and alert an administrator and/or user when excesses occur.
-- Consider investing in telecom expense management tools or services. A baseline look at your options now can help streamline them before numerous iPhone 5s enter your company and can be followed-up with periodic adjustments as needed in the coming months.
-- Consider working with your accounting department to streamline the processing of mobile accounts so you can spot trends quickly, perhaps reviewing them before reconciling/paying them.
-- Set a limit on data service expenses or adjust existing an existing limit -- especially if your company uses a BYOD program where the cost of service is shared between the employee and employer.
-- Work with departments where employees will be upgrading the iPhone 5 to determine which carriers deliver the best coverage and performance. Even if your company is a BYOD-only shop, you can provide this information to users choosing to upgrade on their own.
The new form factor
For the first time in five years, Apple has modified the screen size of the iPhone. The old model had a 3.5-in. screen, the same size the original iPhone had in 2007. The move to a 4-in. screen (which has an 1136-x-640-pixel resolution) forced Apple to make the device just a bit longer, and it meand that any iPhone-oriented tools may need to be revised to take advantage of the extra screen real estate. This isn't as big an issue as adopting the iPad's screen size and existing apps and mobile content will display fine on the new iPhone. But as new in-house native apps and web apps are developed or updated, it's worth considering.
The new Lightning connector
The decision to discard the iPod/iPhone/iPad dock connector and replace it with a newer and smaller port is both a blessing and a curse. Yes, the old connector involved technology that's almost a decade old, but it was also a consistent standard across all of Apple's mobile products. That means iPhone 5 owners will be replacing accessories or buying adapter cables.
Apple has already caught some deserved flack over the pricing of its adapter cables and for not making it clear that the new connection won't deliver all of the functions offered by the old one.