With all of the hardware acceleration options disabled in Chrome, our Core i3-powered Acer TravelMate test system (with 8GB of RAM and Windows 8 Pro) using Chrome v22.0.1229.96 scored 314,359 in BrowserMark, and it managed a frame rate of 16 frames per second in the "Bubbles" benchmark on the IE 10 Testdrive site.
Enabling GPU and threaded compositing in Chrome resulted produced a BrowserMark score of 351,492, but had no impact on the Bubbles benchmark. Enabling the other features (and disabling Vsync) yielded a Browsermark score of 361,687; however, the Bubble benchmark wouldn't render properly and wasn't fully visible on-screen. Reenabling Vsync fixed the Bubble benchmark, and bumped the measured frame rate to 27 fps. Specifically, the Accelerated 2D canvas setting boosted the graphics performance in the Bubbles test.
If you already have a fast system and you keep your software, drivers, and browser version up-to-date, it probably already uses some form of hardware acceleration--and its performance should be quite good. Even so, experimenting with some of the hidden features in Chrome may net some additional performance for free, and that's never a bad thing.